Photo-crosslinkable recombinant collagen mimics for tissue engineering applications. Martins, Christian Rolando, Hugo Thienpont, Heidi Ottevaere, Aleksandr Ovsianikov, Peter Dubruel, Sandra Van Vlierberghe. Qazi, Maxime Vagenende, Fabrice Bray, José C. Liesbeth Tytgat, Marica Markovic, Taimoor H.Engineering a platform for nerve regeneration with direct application to nerve repair technology. The Significance and Utilisation of Biomimetic and Bioinspired Strategies in the Field of Biomedical Material Engineering: The Case of Calcium Phosphat-Protein Template Constructs. Journal of Biomaterials Applications 2020, 34 3-hydroxyvalerate) nanofibrous composite scaffolds for bone regeneration. Aylin Kara, Oylum C Gunes, Aylin Z Albayrak, Gokcen Bilici, Guven Erbil, Hasan Havitcioglu.Materials Science and Engineering: C 2021, 126, 112101. Probiotic bacteria cell surface-associated protein mineralized hydroxyapatite incorporated in porous scaffold: In vitro evaluation for bone cell growth and differentiation. Priya Mullick, Gopal Das, Ramesh Aiyagari.Journal of Colloid and Interface Science 2022, 608, 2298-2309. 2-Dodecylmalonic acid-mediated synthesis of mineralized hydroxyapatite amicable for bone cell growth on orthopaedic implant. Multiphoton Lithography as a Promising Tool for Biomedical Applications. Coralie Greant, Bo Van Durme, Jasper Van Hoorick, Sandra Van Vlierberghe.High-Resolution 3D Bioprinting of Photo-Cross-linkable Recombinant Collagen to Serve Tissue Engineering Applications. Liesbeth Tytgat, Agnes Dobos, Marica Markovic, Lana Van Damme, Jasper Van Hoorick, Fabrice Bray, Hugo Thienpont, Heidi Ottevaere, Peter Dubruel, Aleksandr Ovsianikov, Sandra Van Vlierberghe.This article is cited by 14 publications. Thus, it was shown that architectural cues influence cellular proliferation, while the scaffold chemistry and mechanics independently contribute to gene expression. Further addition of HA, up to 20 wt %, increased osteoblast mineralization, without altering the compressive modulus. Increasing the scaffold mechanical strength, from 2.9 to 5.2 kPa, enhanced the expression of osteocalcin, a late marker of mineralization. Changes in scaffold pore size (150–450 μm) had little effect on mRNA levels but influenced cell proliferation, achieving a balance between nutrient diffusion and surface area for cell attachment at 300 μm. Osteoblast mineralization was assessed, in response to changes in scaffold architecture, hydroxyapatite (HA) content, and mechanics. Utilizing biomimetic nucleation, linear mineralized scaffolds were created from a collagen type I based recombinant peptide (RCP). However, optimization is difficult, due to the complex interplay among architecture, chemistry, and mechanics. Biomineralized scaffolds are an attractive option for bone tissue engineering, being similar to native bone.
0 Comments
Leave a Reply. |
Details
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |